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Related Concept Videos

Fractures: Bone Repair01:27

Fractures: Bone Repair

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Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
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Related Experiment Video

Updated: Apr 19, 2026

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device
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Bone cement augmentation procedures for spinal pathologic fractures by multiple myeloma.

Kee-Yong Ha1, Chang-Ki Min2, Jun-Yeong Seo3

  • 1Department of Orthopedic Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Journal of Korean Medical Science
|January 2, 2015
PubMed
Summary

Bone cement augmentation offers short-term pain relief for spinal fractures in multiple myeloma patients. Radionuclide imaging aids surgical decisions, with procedures showing relative safety in selected cases.

Keywords:
Bone CementsFractures, SpontaneousMultiple MyelomaSpine

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Area of Science:

  • Orthopedics
  • Oncology
  • Radiology

Background:

  • Spinal pathologic fractures are common in multiple myeloma.
  • Current treatment options include conservative management and surgical interventions like bone cement augmentation.
  • The role of radionuclide studies in guiding surgical decisions requires further clarification.

Purpose of the Study:

  • To evaluate the efficacy and safety of bone cement augmentation for spinal fractures in multiple myeloma.
  • To assess the usefulness of radionuclide imaging in surgical decision-making for these fractures.

Main Methods:

  • Retrospective evaluation of 48 vertebrae (bone cement) and 48 vertebrae (conservative treatment) from 27 and 29 patients, respectively.
  • Clinical outcomes assessed using Visual Analogue Scale (VAS) and Oswestry Disability Index (ODI).
  • Radiologic outcomes included vertebral height maintenance and kyphotic angle. Radionuclide studies (bone scan, SPECT) were performed for surgical candidates.

Main Results:

  • Bone cement augmentation provided superior immediate pain relief compared to conservative treatment.
  • The operated group showed better ODI scores, vertebral height maintenance, and local kyphotic angle at follow-up.
  • Cumulative survival rates at one year were similar between groups (77.4% vs. 74.7%). Bone cement leakage occurred in 10 vertebrae.

Conclusions:

  • Bone cement augmentation offers short-term pain relief and functional improvement for spinal pathologic fractures in multiple myeloma.
  • Radionuclide imaging studies are valuable tools for surgical decision-making in these highly selected patients.
  • The procedure demonstrates relative safety with manageable complications like cement leakage.