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Related Experiment Video

Updated: Apr 19, 2026

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

Published on: March 30, 2018

Non-Hodgkin's Malignant Lymphoma with Aggressive Development.

Cezara Elisabeta Danciu¹, Adriana-Daniela Heroiu Cataloiu¹, Cristian Radu Popescu²

¹Department of Otorhinolaryngology, Coltea Clinical Hospital, Bucharest, Romania.

|January 2, 2015

Summary

This case report details an aggressive Non-Hodgkin's lymphoma in a 50-year-old patient. The lymphoma proved resistant to multiple chemotherapy regimens, leading to a rapid and fatal outcome.

Keywords:

NonHodgkin malignant lymphoma aggressive development chemotherapy

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Area of Science:

Hematology
Oncology
Clinical Case Reports

Background:

Non-Hodgkin's malignant lymphoma is a hematologic malignancy.
It typically responds well to polychemotherapy.

Observation:

A 50-year-old patient presented with a large nodal Non-Hodgkin's malignant lymphoma in the neck.
The lymphoma was aggressive in nature.

Findings:

The patient's lymphoma was resistant to three distinct chemotherapy regimens.
Despite treatment, the disease progressed rapidly.

Implications:

This case highlights the challenge of aggressive, treatment-resistant lymphomas.
Further research into novel therapeutic strategies for refractory Non-Hodgkin's lymphoma is warranted.