Outcome of patients with ST segment elevation myocardial infarction (STEMI) following percutaneous transluminal coronary angioplasty: a retrospective study
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Updated: Feb 16, 2026
Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
Published on: May 28, 2019
V Abeysuriya1, L G Chandrasena, A Kasturiratne
1Department of Public Health, Faculty of Medicine, University of Kelaniya, Sri Lanka. visulasrilanka@hotmail.com.
Insights
Patients with ST-elevation myocardial infarction (STEMI) treated with percutaneous coronary intervention (PTCA) had an 83% three-year survival rate. Proximal Left Anterior Descending (LAD) artery occlusion significantly increased mortality risk by 11 times compared to distal occlusion.
Area of Science:
- Cardiology
- Interventional Cardiology
- Public Health
Background:
- ST-elevation myocardial infarction (STEMI) is a critical cardiovascular event.
- Percutaneous coronary intervention (PTCA) is a primary treatment for STEMI.
- Understanding long-term outcomes in diverse healthcare settings is crucial.
Purpose of the Study:
- To assess the characteristics and long-term outcomes of STEMI patients treated with PTCA.
- To identify predictors of mortality in this patient cohort.
- To evaluate outcomes in a fee-levying hospital in Sri Lanka.
Main Methods:
- Retrospective study of 197 STEMI patients treated with PTCA (2009-2012).
- Data collected from medical records, patient interviews, and relative interviews.
- Survival status, cause, and date of death were ascertained.
Main Results:
- Three-year survival rate was 82.7%.
- Proximal Left Anterior Descending (LAD) artery occlusion was associated with an 11-fold increase in all-cause mortality (HR 10.98).
- Low ejection fraction, non-adherence to medication, and delayed treatment (>3 hours) predicted cardiovascular death.
Conclusions:
- STEMI patients undergoing PTCA in Sri Lanka demonstrate an 83% three-year survival.
- Proximal LAD occlusion represents a significant risk factor for long-term mortality post-PTCA.
- Risk stratification and adherence to medication are vital for improving patient outcomes.
Objectives:
To study the characteristics and long term outcome of patients who had segment elevation myocardial infarction (STEMI) and treated with PTCA in a fee levying hospital in Sri Lanka.
Methods:
A retrospective study was conducted among patients diagnosed with STEMI and treated with PTCA in a fee levying private hospital in Colombo from 1st January 2009 to 1st November 2012. Details of patients were obtained from medical records and the survival status, cause of death and date of death where relevant, were obtained from records, patients or close relatives.
Results:
197 patients (153 men; 77.7%) were included. More than 50% had a history of diabetes, dyslipidaemia or hypertension. The three year survival was 82.7% (95% CI: 77.9%-90.5%). Based on the Cox's Proportional Hazards model, site of arterial occlusion (proximal vs distal segment of left anterior descending artery [LAD] was significantly associated with mortality due to all causes [HR 10.98; 95% CI: 1.09-110.20]. Low ejection fraction, not on regular medication and delay of more than 3 hours between onset to door time were associated with death due to cardiovascular causes in patients whose right coronary artery or left circumflex artery was the culprit artery.
Conclusions:
The three year survival of patients with STEMI and who had PTCA was 83%. Patients with proximal LAD occlusion were 11 times more likely to die within 3 years of PTCA as compared to those who had a distal LAD occlusion.
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