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Paediatric infectious diseases: the last 50 years
1Infectious Diseases Unit, Department of General Medicine, Royal Children's Hospital, Melbourne, Victoria, Australia.
Journal of Paediatrics and Child Health
|January 6, 2015
Summary
Paediatric infectious diseases have seen major progress and challenges over 50 years. Key advances include disease eradication and new treatments, while challenges involve emerging infections and antimicrobial resistance.
Area of Science:
- Paediatric Infectious Diseases
- Microbiology
- Immunology
Background:
- The last 50 years have witnessed significant shifts in paediatric infectious diseases.
- A comprehensive review of all advances and challenges is not feasible in a brief format.
Observation:
- Some infectious diseases have virtually disappeared.
- New infectious diseases have emerged.
- Infections in immunocompromised children remain a concern.
Findings:
- Antimicrobial resistance poses a growing threat.
- Development of novel antimicrobials and improved diagnostic tests are crucial.
- The Human Microbiome Project offers new insights into host-pathogen interactions.
Implications:
- Continued vigilance and research are necessary to combat evolving infectious threats in children.
- Advancements in diagnostics and therapeutics are vital for managing paediatric infections.
- Understanding the human microbiome may unlock novel strategies for disease prevention and treatment.
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