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Kizuna is a novel mitotic substrate for CDC25B phosphatase

Yann Thomas1, Marion Peter, Francisca Mechali

  • 1a Centre de Recherche de Biochimie Macromoléculaire (CRBM); ; Montpellier , France.

Cell Cycle (Georgetown, Tex.)
|January 7, 2015
PubMed
Summary

Stabilizing CDC25B phosphatase during mitosis causes cell division errors by disrupting spindle pole integrity. This occurs because CDC25B dephosphorylates Kizuna, a protein crucial for maintaining spindle poles.

Keywords:
CDC25BDMSO, dimethyl-sulfoxydeDSP, Dithiobis [succinimidyl propionate]Kiz, Kizuna proteinKizunaPCM, pericentriolar materialcentrosomemitosis

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