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Updated: Apr 19, 2026

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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Cyclopentyl-pyrimidine based analogues as novel and potent IGF-1R inhibitor

Valmik Aware1, Nitin Gaikwad2, Sambhaji Chavan2

  • 1Department of Medicinal Chemistry, Piramal Enterprises Limited, Goregaon (East), Mumbai 63, India; Organic Chemistry Research Centre, Department of Chemistry, K.R.T. Arts, B.H. Commerce and A.M. Science College, Gangapur Road, Nashik 422 002, MS, India.

European Journal of Medicinal Chemistry
|January 7, 2015
PubMed

Keywords:
Anti-cancerInsulin-like growth factor-1 receptor (IGF-IR)Kinase inhibitorsPyrazolesPyrimidines

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