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Aggressive insulinoma with bone metastases
C S Hesdorffer1, M Stoopler, J Javitch
1Department of Medicine, College of Physicians and Surgeons of Columbia University, New York, New York 10032.
American Journal of Clinical Oncology
|December 1, 1989
Abstract:
This is the first report of the development of bone metastases in a patient with an insulinoma. Following the development of bone metastases, further chemotherapy with etoposide (VP-16) and cis-platinum was not successful and the patient's condition was rapidly fatal. This case demonstrates the unusually aggressive course and poor response to currently available chemotherapeutic agents of a malignant insulinoma. The clinical and diagnostic features of insulinomas are reviewed.