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Changes in preterm human milk composition with particular reference to introduction of mixed feeding
1Division of Neonatology, Department of Pediatrics; and *Department of Biochemistry, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. Correspondence to: Dr Sourabh Dutta, Additional Professor, Division of Neonatology, Advanced Pediatric Centre, PGIMER, Chandigarh 160 012, India. sourabhdutta1@gmail.com.
Objective:
To study the changes in composition of preterm milk till 6 months of age.
Methods:
Milk samples from 33, 19, 7 and 12 lactating mothers (delivered <34 weeks) were analyzed on days 7, 28, 90 and 180, respectively.
Results:
Triglyceride and sodium concentrations increased significantly with time and protein concentration decreased significantly over 180 days. Sodium (P=0.02) and triglyceride concentrations (P=0.06) were higher in milk samples of mothers who had introduced mixed feeding by 6 months post natal age (n=6) compared to exclusively breast-feeding mothers (n=6); but lactose and protein content was not significantly different.
Conclusions:
Milk of preterm mothers has higher amount of triglycerides and sodium during introduction of mixed feeding.
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