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Published on: August 24, 2011
Hematological parameters in adolescents with hyperuricemia
Marian J Stelmach1, Lukasz Szczerbinski, Natalia Wasilewska
1Department of Pediatric Nephrology, Medical University of Bialystok, Poland. Correspondence to: Dr Marian Stelmach, Department of Health and Social Sciences, Pope John Paul II State School of Higher Education, 95/97 Sidorska Street, 21-500 Biala Podlaska, Poland. marian.stelmach@me.com.
Objective:
To examine the association between hematological indices and serum uric acid in adolescents with hyperuricemia.
Methods:
10-year retrospective cohort study of 607 patients with hyperuricemia registered with the Pediatric Nephrology Department.
Results:
There was a statistically significant positive correlation between serum uric acid levels and BMI Z-scores (r=0.406, P<0.001), white and red blood cell counts, hemoglobin and hematocrit. Higher levels of hemoglobin, hematocrit and red blood cells were found in adolescents with metabolic syndrome than in groups without this condition.
Conclusion:
Hematological parameters could be important biological markers of cardiometabolic risk in adolescents with hyperuricemia.
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