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High-alert medications in a French paediatric university hospital
Julie Bataille1, Sonia Prot-Labarthe, Olivier Bourdon
1Hôpital Robert-Debré, APHP, Pharmacie Clinique, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
Insights
This study identified high-alert medications (HAMs) and safety measures for pediatric use. Implementing these strategies, including double-checking prescriptions, aims to reduce medication errors in children.
Area of Science:
- Pediatric Pharmacology
- Patient Safety
- Medication Management
Background:
- High-alert medications (HAMs) pose significant risks of harm when misused.
- Ensuring safe pediatric medication practices is critical.
Purpose of the Study:
- To identify pediatric high-alert medications (HAMs) within an institution.
- To establish comprehensive safety measures for the use of identified HAMs.
Main Methods:
- Literature review to identify HAM classes and specific drugs.
- Survey of healthcare professionals (doctors, nurses, pharmacists) for input.
- Drug steering committee review and selection of HAMs and safety protocols.
Main Results:
- Literature search identified 27 pharmaceutical agent classes and 63 common drug names as HAMs.
- Survey revealed additional HAMs not found in literature, including neuroleptics and IV acetaminophen.
- The drug steering committee finalized a list of 17 pediatric HAMs and 53 safety measures across seven management aspects.
Conclusions:
- Developed a pediatric-specific HAM list and safety measures as part of hospital-wide safety initiatives.
- Safety measures, such as double-checking, require post-implementation review.
- The created list and strategies are adaptable for other pediatric settings to prevent medication errors.
Rationale, Aims And Objectives:
High-alert medications (HAMs) are medications that are associated with a high risk of serious harm if used improperly. The objective of this study was to identify paediatric HAM used in our institution and to identify safety measures for their use.
Methods:
The list of HAM and the list of safety measures that were introduced in our department were based on (1) a literature search; (2) a survey of health care professionals in our department including doctors, head nurses, nurses and pharmacists; and (3) the drug steering committee.
Results:
We found four lists of HAM based on a literature search, including 27 classes of pharmaceutical agents, and 63 common drug names. The response rate of the survey was 20.7% (230 of 1113). Some of the HAMs included in our list were not identified by the literature search. These included neuroleptic drugs, anti-malarial agents, antiviral agents, anti-retroviral agents and intravenous acetaminophen. The drug steering committee selected 17 HAM and highlighted 53 safety measures involving seven broad aspects of pharmacological management.
Conclusions:
This project was part of the new safety strategies developed in a paediatric hospital. We set out to make a list of HAM relevant to paediatrics with additional safety measures to prevent medication errors associated and a 'joker' system. The various safety measures, such as double-checking of HAM prescriptions, should be reviewed during the year following their implementation. This list, which was developed in our hospital specifically for use in paediatrics, can be adapted for use in other paediatric departments.
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