Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Meiosis I01:49

Meiosis I

222.7K
Meiosis is a carefully orchestrated set of cell divisions, the goal of which—in humans—is to produce haploid sperm or eggs, each containing half the number of chromosomes present in somatic cells elsewhere in the body. Meiosis I is the first such division, and involves several key steps, among them: condensation of replicated chromosomes in diploid cells; the pairing of homologous chromosomes and their exchange of information; and finally, the separation of homologous chromosomes by...
222.7K
Teeth01:15

Teeth

2.4K
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
2.4K
Sutures of the Skull01:22

Sutures of the Skull

14.8K
The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
14.8K
Karyotyping01:17

Karyotyping

70.8K
Overview
70.8K
Meiosis vs. Mitosis02:57

Meiosis vs. Mitosis

75.6K
Cell division is necessary for growth and reproduction in organisms. Mitosis aids cell growth and development by dividing somatic cells. In contrast, meiosis causes the division of germ cells and plays an essential role in sexual reproduction. Due to their unique functional requirements, mitosis and meiosis differ from each other in multiple aspects.
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...
75.6K
Changes in the Appendicular Skeleton with Age01:09

Changes in the Appendicular Skeleton with Age

4.1K
The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
4.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Unveiling the Potential of <i>p</i>-Block Bismuth in Homogeneous Electrocatalytic Proton Reduction: Secondary Coordination Sphere Control of Catalytic Activity.

Journal of the American Chemical Society·2026
Same author

Clay pots for reducing fluoride concentration in drinking water.

The Indian journal of medical research·2026
Same author

Invasive Spinal Neuromodulation for Chronic Pain in Pediatric Patients: A Scoping Review.

Pain practice : the official journal of World Institute of Pain·2026
Same author

Manganese-Catalyzed Formate Synthesis via Coupled Methanol Dehydrogenation and Bicarbonate Reduction.

Inorganic chemistry·2026
Same author

Right Atrial Myxoma With Dual Coronary Artery Feeding: A Vascular Surprise.

JACC. Case reports·2026
Same author

Ellis-van Creveld Syndrome: Common Atrium with Post-axial Polydactyly.

QJM : monthly journal of the Association of Physicians·2026

Related Experiment Video

Updated: Apr 18, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
08:03

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model

Published on: November 4, 2025

430

Dentofacial and cranial changes in down syndrome.

Deepika Shukla1, Deepika Bablani1, Aman Chowdhry1

  • 1Department of Oral Pathology and Microbiology, Faculty of Dentistry, Jamia Millia Islamia University, New Delhi, India.

Osong Public Health and Research Perspectives
|January 7, 2015
PubMed
Summary

This study found high rates of dental caries, malocclusion, and periodontal issues in individuals with Down syndrome, highlighting the need for specialized oral healthcare. Oral health status and characteristics were assessed in patients with Down syndrome.

Keywords:
dentofacial anomalydown syndromemacroglossiaoral Hygiene Index

More Related Videos

Quantification of Orofacial Phenotypes in Xenopus
09:26

Quantification of Orofacial Phenotypes in Xenopus

Published on: November 6, 2014

10.4K
In Vitro Modeling of Down Syndrome Neurogenesis Using Human-Induced Pluripotent Stem Cells
06:38

In Vitro Modeling of Down Syndrome Neurogenesis Using Human-Induced Pluripotent Stem Cells

Published on: March 7, 2025

1.1K

Related Experiment Videos

Last Updated: Apr 18, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
08:03

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model

Published on: November 4, 2025

430
Quantification of Orofacial Phenotypes in Xenopus
09:26

Quantification of Orofacial Phenotypes in Xenopus

Published on: November 6, 2014

10.4K
In Vitro Modeling of Down Syndrome Neurogenesis Using Human-Induced Pluripotent Stem Cells
06:38

In Vitro Modeling of Down Syndrome Neurogenesis Using Human-Induced Pluripotent Stem Cells

Published on: March 7, 2025

1.1K

Area of Science:

  • Oral health research
  • Genetics and developmental disorders
  • Public health dentistry

Background:

  • Individuals with Down syndrome often present with unique oral characteristics and health challenges.
  • Understanding these specific oral health needs is crucial for developing targeted interventions.

Purpose of the Study:

  • To determine the prevalence of oral characteristics associated with Down syndrome.
  • To assess the oral health status of patients with Down syndrome.

Main Methods:

  • A cross-sectional study involving clinical examinations and questionnaires.
  • Assessment of oral hygiene (OHI-S), dental caries (DMFT), periodontal status (CPITN), and malocclusion (Angle's classification).
  • Craniometric measurements were taken using Martin spreading calipers.

Main Results:

  • High prevalence of dental caries (78%) and malocclusion (97%, predominantly Class III).
  • Significant periodontal issues (16% requiring complex care) and high need for treatment (90%).
  • Dominant head shapes were brachycephalic and hyperbrachycephalic (90%).

Conclusions:

  • Fissured tongue and macroglossia were the most common dentofacial anomalies.
  • Individuals with Down syndrome exhibit significant oral health deficits requiring comprehensive dental care.