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Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Strategic analytics: towards fully embedding evidence in healthcare decision-making
Jason Garay1, Rosario Cartagena2, Ali Vahit Esensoy3
1Vice-President of Analytics and Informatics at CCO. He is active in the academic community, holding a faculty appointment as Adjunct Professor at the Dalla Lana School of Public Health at the University of Toronto. He has also been a member of several healthcare committees including: President, Association of Public Health Epidemiologists in Ontario; Provincial Co-Chair, Integrated Public Health Information System (iPHIS); National Chair, Pan-Canadian Public Health Epidemiologists' Network; and Executive Board Member, Communicable Diseases Surveillance Network. Jason holds a Master of Health Science in Community Health and Epidemiology from the University of Toronto as well as a BASc in Occupational and Public Health from Ryerson University and an Honours BSc in Statistics and Psychology from York University.
Abstract:
Cancer Care Ontario (CCO) has implemented multiple information technology solutions and collected health-system data to support its programs. There is now an opportunity to leverage these data and perform advanced end-to-end analytics that inform decisions around improving health-system performance. In 2014, CCO engaged in an extensive assessment of its current data capacity and capability, with the intent to drive increased use of data for evidence-based decision-making. The breadth and volume of data at CCO uniquely places the organization to contribute to not only system-wide operational reporting, but more advanced modelling of current and future state system management and planning. In 2012, CCO established a strategic analytics practice to assist the agency's programs contextualize and inform key business decisions and to provide support through innovative predictive analytics solutions. This paper describes the organizational structure, services and supporting operations that have enabled progress to date, and discusses the next steps towards the vision of embedding evidence fully into healthcare decision-making.
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