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Updated: Apr 18, 2026

Isolation and Compositional Analysis of Plant Cuticle Lipid Polyester Monomers
Published on: November 22, 2015
Novel polyacetylenes from Coreopsis tinctoria Nutt
1a Laboratory of Ethnopharmacology , Institute of Nanobiomedical Technology and Membrane Biology, Regenerative Medicine Research Center, West China Hospital/West China Medical School, Sichuan University , Chengdu 610041 , China.
Abstract:
Phytochemical investigation of the 95% EtOH extract of Coreopsis tinctoria Nutt. resulted in the isolation of two novel polyacetylenes, (2S)-(3Z,11E)-decadiene-5,7,9-triyne-1,2-diol (1) and (2R)-(3E,11Z)-decadiene-5,7,9-triyne-1,2-diol (2), together with two known polyacetylenes (3 and 4). The structures of these novel compounds were determined by extensive two-dimensional nuclear magnetic resonance, high-resolution mass spectrometry, and optical rotation. Compounds 1, 2, and 4 were evaluated for their anti-proliferative activities against C26 cell growth and inhibitory effects on the lipo-poly-saccharides-induced nitric oxide production using murine macrophage RAW 264.7 cells. However, compounds 1, 2, and 4 just showed weak activities.
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