Related Experiment Video
Updated: Apr 18, 2026

Author Spotlight: Investigating Early Events and Long-Term Effects of ACL Injuries for Osteoarthritis Progression
Published on: September 29, 2023
Diffusion tensor imaging of the anterior cruciate ligament graft after reconstruction: repeatability and diffusion
Xianfeng Yang1, Dongyang Chen, Ming Li
1From the Departments of *Radiology, and †Orthopedic Surgery, the Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, People's Republic of China.
Purpose:
The purpose of the study was to explore the feasibility and repeatability of diffusion tensor imaging and diffusion tractography on the anterior cruciate ligament graft after reconstruction and determine the fractional anisotropy and mean apparent diffusion coefficient values.
Materials And Methods:
Twenty-two patients who underwent anterior cruciate ligament reconstruction operation were scanned at 3-T clinical magnetic resonance scanner. The fiber tracking and other postprocessing steps were carried out twice by a radiologist on the workstation and repeated by another radiologist. Diffusion tensor metrics of different parts of the grafts were determined with region of interest- and fiber tractography-based measurements, and the intraobserver and interobserver measurement variances were calculated.
Results:
Tractography illustrated nicely the 3-dimensional courses of the graft in all 22 cases. The mean fractional anisotropy value of the intratunnel part was significantly higher than that of the intra-articular part, whereas the mean apparent diffusion coefficient value of the intratunnel part was lower when compared with that of the intra-articular part. According to the 2-sided paired samples Student t test, the intraobserver and interobserver measurements correlated well.
Conclusions:
Diffusion tensor imaging and diffusion tractography can be used to visualize the anterior cruciate ligament grafts and can provide additional information over standard morphologic magnetic resonance imaging.
More Related Videos
06:28Anterior Cruciate Ligament Transection and Synovial Fluid Lavage in a Rodent Model to Study Joint Inflammation and Posttraumatic Osteoarthritis
Published on: September 2, 2025
10:32Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts
Published on: March 26, 2015