Rare complication of silicone fluid injection presenting as multiple calcification and skin defect in both legs: a...

In the past, many materials have been injected for soft tissue augmentation including paraffin (mineral oil) and other non-biocompatible products. Liquid silicone as one of these materials has a long and notorious history as an injectable material for soft tissue augmentation. However, complications, including cellulitis, ulcerations, migration, and nodule formation, have also been reported with silicone injections. This article aims to demonstrate the diagnosis and treatment of multiple calcification and skin defect after silicone fluid injection for soft tissue augmentation. A 65-year-old female presented with skin defect and calcifications had been steadily increasing in size over a 3-month period. Examination confirmed pain, swelling, induration, and 5 × 5 cm sized skin defect with marginal and adjacent calcification in the left lateral malleolar area. She had been injected silicone fluid for soft tissue of lower extremity augmentation and contouring 30 years ago. Serial surgical debridement of this entire zone of calcification and ulceration was undertaken. The defect was closed by a split thickness skin graft. She was satisfied with the aesthetic appearance of the lateral malleolar area, relieving the symptoms of cellulitis.