Related Experiment Video
Updated: Apr 18, 2026

Whole-Body Nanoparticle Aerosol Inhalation Exposures
Published on: May 7, 2013
Occupational diseases in individuals exposed to metal working fluids
1Division of Occupational and Environmental Medicine, Michigan State University, East Lansing, Michigan, USA.
Purpose Of Review:
To examine the current occurrence of respiratory and skin disease in workers who do metal machining with metal working fluids (MWFs), a common work process in manufacturing.
Recent Findings:
A summary of the 27 recognized outbreaks of respiratory disease in workers exposed to MWFs was published. New studies have identified irritative symptoms among workers with low-level exposures. There were review articles discussing the content, measurement and control of microbial agents in MWFs.
Summary:
The occurrence of work-related asthma and hypersensitivity pneumonitis appears to have diminished in the last 10 years. This is presumed to be secondary to lower air levels from the use of newer machining equipment, which are enclosed and have local ventilation as well as better control of microbial contaminants. However, clinicians need to be aware that at the minimum irritative symptoms of the upper respiratory tract are still being reported at these lower exposure levels and there remains the possibility of the development of asthma and hypersensitivity pneumonitis. Given the widespread use of MWFs in manufacturing facilities, clinicians need to consider the possibility that MWFs are the cause or are aggravating the respiratory and dermatologic conditions of their patients.
Related Concept Videos
Types of Toxins
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
Standard Precaution
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
The Periodic Table and Organismal Elements
Acid Mine Drainage
Pleural Effusion II: Symptoms and Management
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
Toxic Reactions: Overview
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...

