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Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis

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Eosinophilic jejunitis presenting as intractable abdominal pain.

Zeynel Mungan¹, Tan Attila¹, Yersu Kapran²

¹Department of Gastroenterology, Koc University School of Medicine, Istanbul, Turkey ; Department of Gastroenterology, American Hospital, Istanbul, Turkey.

Case Reports in Gastroenterology

|January 8, 2015

Summary

Eosinophilic gastroenteritis, a rare gastrointestinal disorder, can cause severe abdominal pain. This case highlights successful steroid treatment for eosinophilic infiltration of the jejunum, avoiding surgery.

Keywords:

Abdominal pain Eosinophilic enteritis Eosinophilic jejunitis

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Area of Science:

Gastroenterology
Pathology

Background:

Eosinophilic gastroenteritis is an uncommon condition involving eosinophilic infiltration of the GI tract.
Clinical symptoms depend on the affected layers and extent of the bowel.

Observation:

A patient presented with intractable abdominal pain.
The pain was attributed to submucosal eosinophilic infiltration in the jejunum, without mucosal involvement.

Findings:

Diagnosis was achieved through deep endoscopic biopsies of the jejunum.
The patient showed a successful response to corticosteroid therapy.

Implications:

This case demonstrates that eosinophilic gastroenteritis can affect deeper layers of the GI tract.
Steroid therapy can be effective in managing this condition, potentially obviating the need for surgical intervention.