Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Block Diagram Reduction01:22

Block Diagram Reduction

678
The process of deriving the transfer function of a control system often involves reducing its block diagram to a single block. This simplification can be achieved through a series of strategic operations, including relocating branch points and comparators. These operations preserve the overall function of the system while allowing for easier manipulation and combination of blocks.
The first step in this process is the identification and relocation of a branch point. A branch point, where a...
678
Neural Circuits01:25

Neural Circuits

3.4K
Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
3.4K
Neurons: The Axon01:21

Neurons: The Axon

14.1K
Axons are long, cytoplasmic processes of nerve cells capable of propagating electrical impulses known as action potentials. The cytoplasm or axoplasm of an axon contains neurofibrils, neurotubules, small vesicles, lysosomes, mitochondria, and various enzymes, all encased within the axolemma, the plasma membrane of the axon.
The axon attaches to the cell body at a cone-shaped elevation called the axon hillock. The initial part of the axon, closest to the hillock, is known as the initial segment....
14.1K
Neuron Structure01:31

Neuron Structure

237.4K
Overview
237.4K
Neuron Structure01:30

Neuron Structure

22.2K
Neurons are the main type of cell in the nervous system that generate and transmit electrochemical signals. They primarily communicate with each other using neurotransmitters at specific junctions called synapses. Neurons come in many shapes that often relate to their function, but most share three main structures: an axon and dendrites that extend out from a cell body.
Structure and Function of Neurons
The neuronal cell body—the soma— houses the nucleus and organelles vital to...
22.2K
Nervous Tissue: Neuron Types01:19

Nervous Tissue: Neuron Types

8.6K
Neurons, the fundamental units of the nervous system, can be classified based on both their structural and functional characteristics.
Structurally, neurons are categorized into three main types: multipolar, bipolar, and unipolar (or pseudounipolar). Multipolar neurons, which are the most common type in the brain and spinal cord, as well as all motor neurons, possess multiple dendrites and a single axon.
Bipolar neurons, on the other hand, have one primary dendrite and one axon. They are...
8.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Structure-preserving model reduction of passive and quasi-active neurons.

Journal of computational neuroscience·2012
Same author

Inverse problems in neuronal calcium signaling.

Journal of mathematical biology·2012
Same author

Morphologically accurate reduced order modeling of spiking neurons.

Journal of computational neuroscience·2010
Same author

Low-dimensional, morphologically accurate models of subthreshold membrane potential.

Journal of computational neuroscience·2009
Same author

Direct correction of non-space-clamped currents via Cole's theorem.

Journal of neuroscience methods·2008
Same author

A kinetic model of oxygen regulation of cytochrome production in Escherichia coli.

Journal of theoretical biology·2006

Related Experiment Video

Updated: Apr 18, 2026

Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches
10:50

Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches

Published on: June 21, 2022

2.3K

Model reduction of strong-weak neurons.

Bosen Du1, Danny Sorensen1, Steven J Cox1

  • 1Department of Computational and Applied Mathematics, Rice University Houston, TX, USA.

Frontiers in Computational Neuroscience
|January 8, 2015
PubMed
Summary
This summary is machine-generated.

This study presents a drastically reduced, highly accurate computational model for neurons. The new model efficiently simulates neuronal function, particularly for collision detection neurons in locusts.

Keywords:
LGMDdiscrete empirical interpolationpredictor-correctorproper orthogonal decompositionquasi-active

More Related Videos

Large-scale Reconstructions and Independent, Unbiased Clustering Based on Morphological Metrics to Classify Neurons in Selective Populations
12:27

Large-scale Reconstructions and Independent, Unbiased Clustering Based on Morphological Metrics to Classify Neurons in Selective Populations

Published on: February 15, 2017

7.5K
Identification and Classification of Position-specific GABAA Receptor Subunit Missense Variants for Their Role In Hippocampal Pyramidal Neurons
08:04

Identification and Classification of Position-specific GABAA Receptor Subunit Missense Variants for Their Role In Hippocampal Pyramidal Neurons

Published on: June 6, 2025

1.8K

Related Experiment Videos

Last Updated: Apr 18, 2026

Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches
10:50

Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches

Published on: June 21, 2022

2.3K
Large-scale Reconstructions and Independent, Unbiased Clustering Based on Morphological Metrics to Classify Neurons in Selective Populations
12:27

Large-scale Reconstructions and Independent, Unbiased Clustering Based on Morphological Metrics to Classify Neurons in Selective Populations

Published on: February 15, 2017

7.5K
Identification and Classification of Position-specific GABAA Receptor Subunit Missense Variants for Their Role In Hippocampal Pyramidal Neurons
08:04

Identification and Classification of Position-specific GABAA Receptor Subunit Missense Variants for Their Role In Hippocampal Pyramidal Neurons

Published on: June 6, 2025

1.8K

Area of Science:

  • Computational neuroscience
  • Neuron modeling

Background:

  • Neurons with large, weakly excitable dendritic trees exhibit attenuated action potentials.
  • Previous models successfully reduced computational size for weakly and strongly excitable neurons separately.

Purpose of the Study:

  • To develop a drastically reduced yet highly accurate computational model for neurons.
  • To combine existing reduction strategies for improved efficiency.

Main Methods:

  • A predictor-corrector decomposition scheme was employed.
  • Integration of reduction techniques for weakly and strongly excitable neuronal components.

Main Results:

  • Achieved a significantly reduced computational model size.
  • Maintained high accuracy in reproducing neuronal input-output mapping.
  • Successfully modeled a caricature of locust collision detection neurons.

Conclusions:

  • The combined reduction strategy offers a powerful approach for efficient and accurate neuron modeling.
  • This method is particularly effective for complex neurons like those involved in sensory processing.