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Updated: Apr 18, 2026

Production and Testing of Antimicrobial Peptides and Their Mimics
Published on: April 10, 2026
Antimicrobial peptides: a new class of antimalarial drugs?
Nuno Vale1, Luísa Aguiar1, Paula Gomes1
1Department of Chemistry and Biochemistry, Faculty of Sciences, Centro de Investigação em Química, University of Porto Porto, Portugal.
Abstract:
A range of antimicrobial peptides (AMP) exhibit activity on malaria parasites, Plasmodium spp., in their blood or mosquito stages, or both. These peptides include a diverse array of both natural and synthetic molecules varying greatly in size, charge, hydrophobicity, and secondary structure features. Along with an overview of relevant literature reports regarding AMP that display antiplasmodial activity, this review makes a few considerations about those molecules as a potential new class of antimalarial drugs.
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