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Axonal regeneration inhibitors: emerging therapeutic options
T W Rosochowicz1, S Wrotek2, W Kozak2
1Nicolaus Copernicus University, Toruń, Poland. trosoch@gmail.com.
Acta Neurologica Belgica
|January 9, 2015
Abstract:
For the most part, the central nervous system is unable to regenerate. The majority of injuries of vascular, inflammatory, degenerative and traumatic aetiology lead to an irreversible loss of central nervous system function. The paper presents the role of Nogo-A, MAG and OMgp proteins in the inhibition of central nervous system regeneration, and their potential clinical significance.

