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[The sympathetic skin response: neurophysiological basis, normal values, clinical applications]
A Uncini1, A Di Muzio, R Cutarella
1Laboratorio di Neurofisiologia Clinica, Università di Chieti.
Rivista Di Neurologia
|May 1, 1989
Summary
The sympathetic skin response (SSR) involves both sensory afferents and central nervous system pathways, not just efferent nerve fibers. This finding broadens understanding of conditions affecting SSR.
Area of Science:
- Neuroscience
- Autonomic Nervous System Physiology
Context:
- The sympathetic skin response (SSR) is a key indicator of autonomic function.
- Its afferent and central pathways remain incompletely understood.
Purpose:
- To investigate the afferent and central components of the sympathetic skin response (SSR).
- To explore the role of myelinated fibers and cortical influence in SSR generation.
Summary:
- SSR was recorded in controls and patients with peripheral neuropathy and stroke using various stimuli.
- Results suggest myelinated fibers act as afferents and the cortex exerts suprasegmental excitatory influence on SSR.
- Absence of SSR may stem from efferent, afferent, or central pathway dysfunction.
Impact:
- This research expands the diagnostic considerations for unobtainable SSR.
- It highlights the complex neural circuitry underlying autonomic responses.
- Findings contribute to a deeper understanding of neurological and autonomic disorders.