Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Symbiosis

Symbiosis

Symbiotic relationships are long-term, close interactions between individuals of different species that affect the distribution and abundance of those species. When a relationship is beneficial to both species, this is called mutualism. When the relationship is beneficial to one species but neither beneficial nor harmful to the other species, this is called commensalism. When one organism is harmed to benefit another, the relationship is known as parasitism. These types of relationships often...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Parasitic infection and resource acquisition shape senescence through oxidative stress and energy depletion.

Evolution; international journal of organic evolution·2026

Same author

Testing the redox theory of aging under parasitism.

npj aging·2026

Same author

Effects of a caffeine-based diet on insecticide resistance and longevity in infected Anopheles coluzzii.

Parasites & vectors·2026

Same author

Phenotypic variation in populations of the mosquito vector, Aedes aegypti, and implications for predicting the effects of temperature and climate change on dengue transmission.

PLoS neglected tropical diseases·2025

Same author

Energetic shifts reflect survival likelihood in Anopheles gambiae.

Communications biology·2025

Same author

Dietary shifts in infected mosquitoes suggest a form of self-medication despite benefits in uninfected individuals.

Proceedings. Biological sciences·2025

Same journal

Incorporating Population Genomic Perspectives Into Kelp Conservation and Aquaculture in the Pacific Northwest.

Evolutionary applications·2026

Same journal

Multidisciplinary Evaluation of a 10-Year Restoration Program for Two Endangered Atlantic Salmon (<i>Salmo salar</i>) Populations.

Evolutionary applications·2026

Same journal

Tuberculosis Susceptibility and Inbreeding Depression Hinder <i>Ex Situ</i> Conservation in a Critically Endangered Rainforest Bird.

Evolutionary applications·2026

Same journal

Altitude-Associated Divergence of the Gut Microbiome in Endangered Forest Musk Deer: Evidence From Integrated Metagenomics, Metabolomics, and Culturomics.

Evolutionary applications·2026

Same journal

Evolutionary Footprint: A Systemic Indicator in Evolution, Ecology and Conservation.

Evolutionary applications·2026

Same journal

Integrating Ultimate and Proximate Explanations of Neurodivergence: Evolutionary Trade-Offs, Compensation, and Clinical Expression.

Evolutionary applications·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 18, 2026

Protocols for Testing the Toxicity of Novel Insecticidal Chemistries to Mosquitoes

Protocols for Testing the Toxicity of Novel Insecticidal Chemistries to Mosquitoes

Published on: February 13, 2019

Towards evolution-proof malaria control with insecticides.

Jacob C Koella¹, Penelope A Lynch², Matthew B Thomas³

¹Division of Biology, Imperial College London Ascot, UK.

Evolutionary Applications

|January 9, 2015

Summary

This summary is machine-generated.

Developing novel malaria control strategies by using insecticides that target adult mosquitoes later in their life cycle can delay or prevent insecticide resistance, promoting sustainable disease control.

Keywords:

benefit of resistance evolution-proof control insecticide resistance late-acting insecticide malaria control

More Related Videos

Microinjection Method for Anopheles gambiae Embryos

Microinjection Method for Anopheles gambiae Embryos

Published on: July 7, 2021

Ookluc: A Plasmodium berghei Line for Identifying Transmission-blocking Compounds

Ookluc: A Plasmodium berghei Line for Identifying Transmission-blocking Compounds

Published on: July 11, 2025

Related Experiment Videos

Last Updated: Apr 18, 2026

Protocols for Testing the Toxicity of Novel Insecticidal Chemistries to Mosquitoes

Protocols for Testing the Toxicity of Novel Insecticidal Chemistries to Mosquitoes

Published on: February 13, 2019

Microinjection Method for Anopheles gambiae Embryos

Microinjection Method for Anopheles gambiae Embryos

Published on: July 7, 2021

Ookluc: A Plasmodium berghei Line for Identifying Transmission-blocking Compounds

Ookluc: A Plasmodium berghei Line for Identifying Transmission-blocking Compounds

Published on: July 11, 2025

Area of Science:

Vector-borne disease control
Insecticide resistance evolution
Malaria epidemiology

Background:

Current malaria control relies heavily on insecticides targeting adult mosquitoes.
The evolution of insecticide resistance in mosquito populations undermines control efficacy.
Understanding mosquito lifespan and parasite development is crucial for effective malaria control.

Purpose of the Study:

To propose novel insecticide strategies to delay or prevent the evolution of mosquito resistance.
To explore the combined use of late-acting insecticides and larvicides for sustainable malaria control.
To investigate the potential benefits of resistance evolution to larvicides under specific conditions.

Main Methods:

Analysis of epidemiological principles related to mosquito lifespan and malaria transmission.
Application of evolutionary principles concerning selection pressure on different age groups.
Theoretical modeling of insecticide efficacy and resistance evolution under various control scenarios.

Main Results:

Insecticides with delayed action (killing mosquitoes days after exposure) can significantly slow resistance evolution.
Resistance to larvicides can be beneficial if it correlates with reduced adult lifespan or biting rates.
Combining late-acting insecticides with larvicides may prevent resistance to the more effective insecticide.

Conclusions:

Strategic use of insecticides, particularly those with delayed effects, can enhance malaria control sustainability.
Larvicides, when used in conjunction with late-acting agents, can play a role in preventing resistance.
Biopesticides offer a promising avenue for developing novel, late-acting insecticides to combat malaria.