Related Experiment Video
Updated: Apr 18, 2026
07:54
Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
Published on: December 21, 2019
7.4K
Global mesothelioma epidemic: Trend and features
Claudio Bianchi1, Tommaso Bianchi1
1Center for the Study of Environmental Cancer, Italian League Against Cancer, Monfalcone, Italy.
Indian Journal of Occupational and Environmental Medicine
|January 9, 2015
Summary
The mesothelioma epidemic continues to rise globally, with high incidence rates in Europe and Oceania. More data is needed to understand the full scope and raise awareness of asbestos risks.
Area of Science:
- Epidemiology
- Public Health
Background:
- Mesothelioma incidence is increasing globally, presenting an epidemic trend.
- The current trajectory of this epidemic is not well-defined.
Purpose of the Study:
- To gather recent mesothelioma incidence data.
- To ascertain the current trend of the mesothelioma epidemic.
Main Methods:
- Review of Cancer and Mesothelioma Registries.
- Contacting researchers for supplementary data.
Main Results:
- Highest incidence rates observed in the UK, Netherlands, Malta, Belgium, Australia, and New Zealand.
- Increasing incidence trends noted in many countries.
- Low incidence/mortality rates in Japan and Central Europe; data gaps exist for populous nations.
Conclusions:
- The mesothelioma epidemic shows no signs of decreasing.
- Insufficient global data hinders awareness of asbestos exposure risks.
Related Concept Videos
01:30Pleural Disorders: Types and Brief Description
1.0K
The pleura is a vital part of the respiratory system. It's a double-layered membrane surrounding the lungs and lining the chest cavity. The two layers of the pleura are:
1.0K
01:21Barrett Esophagus-I: Introduction
1.4K
Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
1.4K
02:30Metastasis
7.0K
Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
7.0K
02:38Mitogens and the Cell Cycle
8.5K
Mitogens and their receptors play a crucial role in controlling the progression of the cell cycle. However, the loss of mitogenic control over cell division leads to tumor formation. Therefore, mitogens and mitogen receptors play an important role in cancer research. For instance, the epidermal growth factor (EGF) - a type of mitogen and its transmembrane receptor (EGFR), decides the fate of the cell's proliferation. When EGF binds to EGFR, a member of the ErbB family of tyrosine kinase...
8.5K
02:17The Tumor Microenvironment
8.3K
Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
8.3K