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Establishing a Mouse Contusion Spinal Cord Injury Model Based on a Minimally Invasive Technique
Published on: September 7, 2022
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Radiation-induced spinal cord hemorrhage (hematomyelia)
Amit Agarwal1, Sangam Kanekar2, Krishnamurthy Thamburaj1
1Department of Radiology, Penn State University Hershey , PA, USA.
Neurology International
|January 9, 2015
Summary
Radiation-induced hematomyelia is an extremely rare spinal cord injury. This case highlights a rare instance in an 8-year-old girl with Ewing's sarcoma, emphasizing the need for vigilant diagnosis.
Area of Science:
- Neurology
- Oncology
- Radiology
Background:
- Intraspinal hemorrhage, particularly intramedullary hemorrhage (hematomyelia), is rare, often linked to trauma.
- Spinal vascular malformations are the primary cause of non-traumatic hematomyelia.
- Other causes include anticoagulation, bleeding disorders, and spinal cord tumors.
Observation:
- This report details an exceptionally rare case of radiation-induced hematomyelia.
- The patient was an 8-year-old girl diagnosed with Ewing's sarcoma of the thoracic vertebra undergoing radiation therapy.
- She presented with symptoms indicative of hematomyelia.
Findings:
- The case describes the clinical progression and imaging results of radiation-induced hematomyelia.
- Literature review confirms the extreme rarity, with only one prior reported case.
- The study emphasizes the importance of recognizing spinal cord injury patterns.
Implications:
- Clinicians should consider radiation-induced hematomyelia in patients undergoing spinal radiation therapy.
- Prompt imaging is crucial for diagnosing compressive spinal cord pathologies.
- This case expands the understanding of rare adverse effects of cancer treatment.
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