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Updated: Apr 18, 2026

Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis
Published on: March 4, 2014
Pincer nail deformity in a patient with amyotrophic lateral sclerosis
Youshi Fujita1, Takehisa Fujita1
1Fujita Neurological Hospital , Fukui, Japan.
Abstract:
Although several manifestations of skin involvement in cases of amyotrophic lateral sclerosis (ALS) have been reported, the pincer nail deformity has not been previously reported in a patient with ALS. The pincer nail deformity is characterized by distortion of the shape of the nail with transverse over curvature and may be associated with systemic diseases and certain medications. We herein describe the case of a patient presenting with a pincer nail deformity associated with rapidly advancing ALS. This case suggests a potential link between quickly advancing disease and the pincer nail deformity.
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