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Related Concept Videos

Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

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The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
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Association Areas of the Cortex01:21

Association Areas of the Cortex

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Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
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Spinal Cord: Cross-sectional Anatomy01:16

Spinal Cord: Cross-sectional Anatomy

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The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
Gray Matter and its Components
Central to the gray matter is...
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Somatosensory, Motor, and Association Cortex01:23

Somatosensory, Motor, and Association Cortex

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The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
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Cerebrum: Anatomical Overview II01:11

Cerebrum: Anatomical Overview II

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Each cerebral hemisphere can be divided into three main regions. The outermost region, the cerebral cortex, is a thin layer (2 to 4 millimeters thick) made up of gray matter, consisting of neuron cell bodies, dendrites, glial cells, and blood vessels. The middle region, or white matter, is primarily composed of myelinated nerve fibers organized into three types of large tracts: association fibers, commissures, and projection fibers. Association fibers connect different areas within the same...
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Functional Brain Systems: Reticular Formation01:13

Functional Brain Systems: Reticular Formation

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The reticular formation is a complex network of gray and white matter located within the brainstem extending from the medulla to the midbrain.
Within the reticular formation, there are several distinct nuclei that can be classified into three broad categories. The Raphe nuclei are located along the midline of the brainstem. They are primarily known for their role in synthesizing and releasing serotonin, a neurotransmitter involved in regulating mood, appetite, sleep, and circadian rhythms. The...
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Related Experiment Video

Updated: Apr 18, 2026

Fiber Connections of the Supplementary Motor Area Revisited: Methodology of Fiber Dissection, DTI, and Three Dimensional Documentation
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Fiber Connections of the Supplementary Motor Area Revisited: Methodology of Fiber Dissection, DTI, and Three Dimensional Documentation

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Functionally defined white matter reveals segregated pathways in human ventral temporal cortex associated with

Jesse Gomez1, Franco Pestilli2, Nathan Witthoft3

  • 1Neurosciences Program, Stanford University School of Medicine, Stanford, CA 94305, USA.

Neuron
|January 9, 2015
PubMed
Summary
This summary is machine-generated.

White matter pathways in the brain connect visual networks. Their structure influences face and place recognition, with abnormalities linked to face blindness (developmental prosopagnosia).

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Area of Science:

  • Neuroscience
  • Cognitive Neuroscience
  • Neuroimaging

Background:

  • The relationship between white-matter properties and category-specific visual processing remains unclear.
  • Understanding how anatomical connectivity supports specialized visual functions is crucial.

Purpose of the Study:

  • To investigate if white-matter structure in specific visual networks selectively impacts category-specific processing.
  • To explore the link between white-matter pathways, functional selectivity, and behavioral performance in visual tasks.

Main Methods:

  • Combined white-matter structure (diffusion MRI) and functional selectivity (fMRI) measurements in the same individuals.
  • Correlated diffusion properties of white-matter tracts with behavioral performance in face and place recognition tasks.
  • Examined individuals with developmental prosopagnosia to assess structure-behavior relationships.

Main Results:

  • Identified two parallel white-matter pathways in the ventral temporal lobe connecting to face- and place-selective regions.
  • Diffusion properties of these tracts correlated with behavioral performance for face or place processing.
  • Adults with developmental prosopagnosia showed atypical structure-behavior relationships near face-selective cortex.

Conclusions:

  • White-matter pathways adjacent to category-selective regions are functionally relevant for visual processing.
  • Atypicalities in white matter structure near face-selective cortex may contribute to developmental prosopopagnosia.
  • Interplay between cortical function, anatomical connectivity, and behavior is key to understanding visual abilities and deficits.