Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Apr 18, 2026

Rapid Analysis and Exploration of Fluorescence Microscopy Images
11:41

Rapid Analysis and Exploration of Fluorescence Microscopy Images

Published on: March 19, 2014

12.9K

Visualizing cellular imaging data using PhenoPlot.

Heba Z Sailem1, Julia E Sero1, Chris Bakal1

  • 1Dynamical Cell Systems, Division of Cancer Biology, Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, UK.

Nature Communications
|January 9, 2015
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neuroblastoma: Anti-Invasive Effects of Tetracaine In Vitro.

Basic & clinical pharmacology & toxicology·2026
Same author

High content 3D imaging by dual-view oblique plane microscopy.

PNAS nexus·2025
Same author

Stabilizing a Native Fold of Alpha-Synuclein with Short Helix-Constrained Peptides.

JACS Au·2025
Same author

Structural Identification of Major Molecular Determinants for Phosphotyrosine Recognition in Tyrosine Kinases Reveals Tumour Promoting and Suppressive Functions.

bioRxiv : the preprint server for biology·2025
Same author

The PARP inhibitor talazoparib synergizes with reovirus to induce cancer killing and tumour control in vivo in mouse models.

Nature communications·2025
Same author

Integration of focal adhesion morphogenesis and polarity by DOCK5 promotes YAP/TAZ-driven drug resistance in TNBC.

Molecular omics·2025
Same journal

Demonstration of a quantum C-NOT gate in a time-multiplexed fully reconfigurable photonic processor.

Nature communications·2026
Same journal

Nonlinear quantum light source with van der Waals ferroelectric NbOX<sub>2</sub> (X = Br, I).

Nature communications·2026
Same journal

Antagonistic histone H2A variants and autonomous heterochromatin formation shape epigenomic patterns in Arabidopsis.

Nature communications·2026
Same journal

The long tail of nitrate pollution in groundwater challenges governance of global water quality.

Nature communications·2026
Same journal

Select microbial metabolites promote tau aggregation in a murine tauopathy model.

Nature communications·2026
Same journal

Warming climate has lengthened global intense tropical cyclone seasons.

Nature communications·2026
See all related articles

High-content analysis generates complex cellular data. PhenoPlot visualizes this quantitative imaging data using interpretable glyphs, enhancing the exploration of cellular phenotypes, particularly in breast cancer research.

Area of Science:

  • Biomedical imaging
  • Computational biology
  • Data visualization

Background:

  • High-content analysis generates complex, high-dimensional datasets describing cellular phenotypes.
  • Existing visualization methods are insufficient for interpreting these complex image-derived datasets.
  • Effective visualization is crucial for data interpretation and hypothesis generation in biological research.

Purpose of the Study:

  • To introduce PhenoPlot, a novel visualization tool for quantitative high-content imaging data.
  • To demonstrate PhenoPlot's utility in exploring and interpreting complex cellular phenotypes.
  • To address the paucity of visualization methods for high-dimensional image-derived data.

Main Methods:

  • Development of PhenoPlot, a software tool for data visualization.

More Related Videos

Droplet Barcoding-Based Single Cell Transcriptomics of Adult Mammalian Tissues
10:12

Droplet Barcoding-Based Single Cell Transcriptomics of Adult Mammalian Tissues

Published on: January 10, 2019

19.2K
Fabrication of a Multiplexed Artificial Cellular MicroEnvironment Array
07:19

Fabrication of a Multiplexed Artificial Cellular MicroEnvironment Array

Published on: September 7, 2018

9.2K

Related Experiment Videos

Last Updated: Apr 18, 2026

Rapid Analysis and Exploration of Fluorescence Microscopy Images
11:41

Rapid Analysis and Exploration of Fluorescence Microscopy Images

Published on: March 19, 2014

12.9K
Droplet Barcoding-Based Single Cell Transcriptomics of Adult Mammalian Tissues
10:12

Droplet Barcoding-Based Single Cell Transcriptomics of Adult Mammalian Tissues

Published on: January 10, 2019

19.2K
Fabrication of a Multiplexed Artificial Cellular MicroEnvironment Array
07:19

Fabrication of a Multiplexed Artificial Cellular MicroEnvironment Array

Published on: September 7, 2018

9.2K
  • Representation of high-dimensional feature vectors as interpretable glyphs.
  • Application of PhenoPlot to analyze complex breast cancer cell phenotypes.

    • Main Results:

    • PhenoPlot effectively represents quantitative high-content imaging data.
    • The tool generates easily interpretable glyphs from complex cellular feature vectors.
    • PhenoPlot facilitates improved exploration and interpretation of breast cancer cell phenotypes.

    Conclusions:

    • PhenoPlot offers a valuable solution for visualizing complex high-content imaging data.
    • The tool enhances the understanding of cellular phenotypes derived from image analysis.
    • PhenoPlot has potential applications in various fields utilizing high-content screening and imaging data.