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Related Concept Videos

Antiasthma Drugs: β2-Adrenoceptor Agonists01:25

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Bronchodilators are critical in managing asthma, a chronic respiratory condition characterized by airway constriction due to inflammation and hyper-reactivity. Specifically, bronchodilators ease this constriction by relaxing the bronchial muscles, facilitating easier breathing.
One class of bronchodilators includes β2-adrenoceptor agonists. These agents target the β2-adrenoceptors located on bronchial smooth muscle cells. By stimulating these receptors, β2-agonists induce...
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Asthma-I: Introduction01:29

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Clinical Assessment for Asthma:
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Inhaled medications are crucial for managing chronic obstructive pulmonary disease (COPD) and asthma. They are essential for effective treatment and control, ensuring optimal respiratory health and well-being. Inhaled medication delivers drugs directly to the lungs, providing a rapid onset of action and reducing systemic side effects compared to oral or injectable medications. Three primary types of inhalation devices are used to administer these medications: nebulizers, metered-dose inhalers...
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The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
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Asthma-III: Symptoms and Complications01:24

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Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
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Related Experiment Video

Updated: Apr 18, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
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Primary adherence to controller medications for asthma is poor.

Ann Chen Wu1, Melissa G Butler, Lingling Li

  • 11 Center for Child Health Care Studies, Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School.

Annals of the American Thoracic Society
|January 9, 2015
PubMed
Summary
This summary is machine-generated.

Asthma controller medication adherence is poor, with 14-20% of patients not filling initial prescriptions. Primary adherence to inhaled corticosteroids (ICSs) was better than leukotriene antagonists (LTRAs) and ICS/long-acting beta-agonists (ICS/LABAs).

Keywords:
adherenceasthmainhaled corticosteroidsleukotriene antagonistsmedications

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Area of Science:

  • Pulmonary Medicine
  • Pharmacology
  • Health Services Research

Background:

  • Persistent asthma requires consistent controller medication use.
  • Primary adherence to controller medications is understudied.
  • Evaluating adherence across major asthma medication classes is crucial.

Purpose of the Study:

  • To compare primary adherence and medication coverage across key asthma controller regimens.
  • To identify factors influencing adherence in a large, insured population.

Main Methods:

  • Retrospective cohort study utilizing electronic health records from five large health plans.
  • Included patients of all ages with a prior asthma exacerbation.
  • Assessed adherence using proportion of days covered (PDC) and primary adherence (prescription filled within 30 days).

Main Results:

  • 14-20% of patients with probable persistent asthma did not fill their first controller prescription.
  • Mean PDC over 12 months: 19% for inhaled corticosteroids (ICSs), 30% for leukotriene antagonists (LTRAs), and 25% for ICS/long-acting beta-agonists (ICS/LABAs).
  • Leukotriene antagonists (LTRAs) showed lower primary adherence than ICSs and ICS/LABAs; Black and Latino patients had lower adherence.

Conclusions:

  • Adherence to asthma controller medications is generally poor.
  • Inhaled corticosteroids (ICSs) demonstrated better primary adherence compared to LTRAs and ICS/LABAs.
  • Leukotriene antagonists (LTRAs) and ICS/LABAs showed better adherence by proportion of days covered (PDC) than ICSs.