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A multi-parameters fusion model for non-invasive detection of intracranial pressure

Zhong Ji, Xu Liu

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |January 9, 2015
    PubMed

    Abstract:

    On the basis of discussing the limitation of a single intracranial pressure non-invasive detection method in clinical application, the feasibility of the measurement and analysis model is investigated based on multi-parameters organic integration facing to intracranial pressure non-invasive measurement. Then the sensitivity analysis for the relation between the detected parameters and the change of intracranial pressure will be done. Finally, a synthesized non-invasive evaluation frame for intracranial pressure measurement with disease-adaptive model choice will be realized. By this way, a new idea is provided for the realization of the non-invasive measurement of intracranial pressure and its clinical application, which will be of significance for improving the clinical feasibility and monitoring accuracy of intracranial pressure non-invasive measuring methods.

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    Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component...
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