Related Experiment Videos
Role of supernumerary subunits in mitochondrial cytochrome c oxidase
Y Planques1, N Capitanio, G Capitanio
1Institute of Medical Biochemistry and Chemistry, University of Bari, Italy.
FEBS Letters
|December 4, 1989
Abstract:
Role of supernumerary subunits of bovine heart cytochrome c oxidase has been investigated by examining the influence on the enzymatic activity of their removal by chromatographic procedures or controlled digestion by trypsin. Is has been shown that partial proteolytic cleavage of subunit IV results in depression of respiratory activity and of redox-linked proton translocation. Selective removal by gel-filtration of subunit Vlb has no significant influence on the redox and protonmotive activity of the oxidase.