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Relationship between white matter hyperintensities, cortical thickness, and cognition

Anil M Tuladhar1, Andrew T Reid1, Elena Shumskaya1

  • 1From the Department of Neurology, Center for Neuroscience (A.M.T., A.G.W.v.N., E.J.v.D., F.-E.d.L.), Centre for Cognitive Neuroimaging (E.S., D.G.N.), Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands; Institute of Neuroscience and Medicine (INM-1), Research Center Julich, Julich, Germany (A.T.R.); Department of Neurology, HagaZiekenhuis Den Haag, Den Haag, The Netherlands (K.F.d.L.); Erwin L. Hahn Institute for Magnetic Resonance Imaging, University of Duisburg-Essen, Essen, Germany (D.G.N.); and MIRA Institute for Biomedical Technology and Technical Medicine, University of Twente, Enschede, The Netherlands (D.G.N.).

Stroke
|January 10, 2015
PubMed
Summary

White matter hyperintensities (WMH) are linked to brain structure changes and cognitive decline in small vessel disease. Cortical thickness and network disruptions, not just WMH, explain cognitive impairment.

Keywords:
cognition

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