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Updated: Apr 18, 2026

Evaluation of Vascular Control Mechanisms Utilizing Video Microscopy of Isolated Resistance Arteries of Rats
Published on: December 5, 2017
Correlation and spectral analysis of vascular tone regulator mechanisms in paired formations during postnatal
L A Mikhailichenko1, L V Mezentseva
1Research Institute of General Pathology and Pathological Physiology, Moscow, Russia.
Abstract:
The study focused on the changes of microcirculation indices and components of the vascular tone of endothelial, neural, and myogenic nature in symmetrical skin sites of temples, forehead, auricles, scapulae, and groin during postnatal ontogeny. Initially, microcirculation indices in the symmetrical regions decreased to postnatal day 10, thereafter they surpassed the initial level at the age of 30 days. The endothelial, neural, and myogenic indices of vascular tone changed differently in the symmetrical left and right sites. On the right side, all indices increased by the postnatal day 21 ("redundancy" phase), and by postnatal day 30 surpassed the initial level by two times. On the left side, the redundancy phase manifested in the endothelial component on postnatal day 10, but to postnatal day 30 all three indices dropped below the initial level.
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