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Related Concept Videos

Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

Mitral Stenosis II: Clinical features and Diagnostic Tests

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Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
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Cushing Syndrome I: Introduction01:26

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Cushing syndrome refers to the collection of clinical manifestations that arise when tissues are exposed to excessive amounts of cortisol or cortisol-like medications over an extended period. Cortisol, a glucocorticoid produced by the adrenal cortex, regulates metabolism, immune responses, and the body’s adaptation to stress. When its concentration remains chronically elevated, these physiological pathways become dysregulated, resulting in the characteristic features of the...
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Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

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The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
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Esophageal Strictures-II: Clinical Features and Management01:26

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Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
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Cushing Syndrome II: Pathophysiology01:19

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Cortisol production is normally governed by the hypothalamic–pituitary–adrenal (HPA) axis, which maintains hormonal balance through tightly regulated feedback mechanisms. Disruption of this regulatory system is central to the development of Cushing syndrome, whether the excess cortisol originates from external medications or internal pathology. Persistent cortisol elevation alters metabolism, immune function, and endocrine signaling, producing the characteristic clinical features...
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Mitral Stenosis I: Introduction01:22

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Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
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Establishment of a Modified Ferric Chloride-Induced Superior Sagittal Sinus Thrombosis
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Stewart-Treves syndrome: a case report.

Anis Benmansour1, Saad Laanaz2, Abdeslam Bougtab1

  • 1Department of Surgical Oncology, National Institute of Oncology, Rabat, Morocco.

The Pan African Medical Journal
|January 10, 2015
PubMed
Summary

Stewart-Treves syndrome is a rare angiosarcoma that develops in limbs with chronic lymphedema, often after mastectomy. Early diagnosis and radical surgery offer the best prognosis for this aggressive cancer.

Keywords:
Stewart–Trevesangiosarcomasyndrome

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Area of Science:

  • Oncology
  • Dermatology
  • Surgical Pathology

Background:

  • Stewart-Treves syndrome is a rare angiosarcoma arising from chronic lymphedema.
  • It most frequently occurs after radical mastectomy for breast cancer.

Observation:

  • A case of Stewart-Treves syndrome in a 66-year-old woman, 10 years post-mastectomy, is presented.
  • Diagnosis was confirmed via skin biopsy.
  • The patient's angiosarcoma was deemed unresectable at diagnosis.

Findings:

  • Radical surgery remains the primary curative treatment for Stewart-Treves syndrome.
  • Conservative surgery with adjuvant radiotherapy is an alternative.
  • Systemic chemotherapy is indicated for advanced, unresectable, or metastatic disease.

Implications:

  • Long-term follow-up of post-mastectomy lymphedema is crucial for early detection.
  • Timely diagnosis and treatment are vital for improving the poor prognosis associated with this condition.