Central giant cell lesion: diagnosis to rehabilitation

Central giant cell lesion (CGCL) is a benign bone lesion of unknown etiology that primarily affects the mandible, with a predilection for female children and young adults. This article describes a case of a 16-year-old boy with a palatal swelling of approximately 18 months duration. Clinical, radiographic, histopathological, and hematological examinations led to a diagnosis of CGCL. Treatment involved a complete enucleation of the lesion and the removal of several teeth. A subsequent esthetic/functional rehabilitation was performed using a removable prosthesis. The patient was submitted to rigorous clinical and radiographic follow-ups, with no signs of recurrence over a 7-year period.