Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Atomic Nuclei: Nuclear Spin01:08

Atomic Nuclei: Nuclear Spin

5.9K
All atomic particles possess an intrinsic angular momentum, or 'spin'. Electrons, protons, and neutrons each have a spin value of ½, although protons and neutrons in nuclei may have higher half-integer spins owing to energetic factors.
Atomic nuclei have a net nuclear spin, , which can have an integer or half-integer value. In atomic nuclei, the spins of protons are paired against each other but not with neutrons, and vice versa. Consequently, an even number of protons does not contribute...
5.9K
Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)01:20

Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)

2.0K
Two NMR-active nuclei bonded to a central atom can be involved in geminal or two-bond coupling. Geminal coupling is commonly seen between diastereotopic protons in chiral molecules and unsymmetrical alkenes, among others.
The central atom need not be NMR-active because its electrons are affected by the electron polarization of the spin-active atoms. However, spin information is transmitted less effectively than in one-bond coupling, and 2J values are usually weaker than 1J values. The energy of...
2.0K
Spin–Spin Coupling: One-Bond Coupling01:17

Spin–Spin Coupling: One-Bond Coupling

1.7K
Coupling interactions are strongest between NMR-active nuclei bonded to each other, where spin information can be transmitted directly through the pair of bonding electrons. While nuclei polarize their electrons to the opposite spins, the bonding electron pair has opposite spins. Configurations with antiparallel nuclear spins are expected to be lower in energy. When coupling makes antiparallel states more favorable, J is considered to have a positive value. The one-bond coupling constant, 1J,...
1.7K
Organic Compounds03:02

Organic Compounds

59.2K
All living things are formed mostly of carbon compounds called organic compounds. The category of organic compounds includes both natural and synthetic compounds that contain carbon. Although a single, precise definition has yet to be identified by the chemistry community, most agree that a defining trait of organic molecules is the presence of carbon as the principal element, bonded to hydrogen and other carbon atoms. However, some carbon-containing compounds such as carbonates, cyanides, and...
59.2K
Valence Bond Theory02:42

Valence Bond Theory

11.9K
Coordination compounds and complexes exhibit different colors, geometries, and magnetic behavior, depending on the metal atom/ion and ligands from which they are composed. In an attempt to explain the bonding and structure of coordination complexes, Linus Pauling proposed the valence bond theory, or VBT, using the concepts of hybridization and the overlapping of the atomic orbitals. According to VBT, the central metal atom or ion (Lewis acid) hybridizes to provide empty orbitals of suitable...
11.9K
NMR Spectroscopy: Spin–Spin Coupling01:08

NMR Spectroscopy: Spin–Spin Coupling

3.9K
The spin state of an NMR-active nucleus can have a slight effect on its immediate electronic environment. This effect propagates through the intervening bonds and affects the electronic environments of NMR-active nuclei up to three bonds away; occasionally, even farther. This phenomenon is called spin–spin coupling or J-coupling. Coupling interactions are mutual and result in small changes in the absorption frequencies of both nuclei involved. While nuclei of the same element are involved...
3.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Towards Metabolic Organic Radical Contrast Agents (mORCAs) for Magnetic Resonance Imaging.

Molecules (Basel, Switzerland)·2025
Same author

Radical-Induced Changes in Transition Metal Interfacial Magnetic Properties: A Blatter Derivative on Polycrystalline Cobalt.

Angewandte Chemie (International ed. in English)·2024
Same author

Chiral π-Conjugated Double Helical Aminyl Diradical with the Triplet Ground State.

Journal of the American Chemical Society·2024
Same author

Cucurbit[7]uril Enhances Distance Measurements of Spin-Labeled Proteins.

Journal of the American Chemical Society·2023
Same author

From Stable Radicals to Thermally Robust High-Spin Diradicals and Triradicals.

Chemical reviews·2023
Same author

Cucurbit[7]uril Enhances Distance Measurements of Spin-Labeled Proteins.

bioRxiv : the preprint server for biology·2023

Related Experiment Video

Updated: Apr 18, 2026

Light-driven Molecular Motors on Surfaces for Single Molecular Imaging
08:40

Light-driven Molecular Motors on Surfaces for Single Molecular Imaging

Published on: March 13, 2019

12.2K

High-spin organic molecules.

Nolan M Gallagher1, Arnon Olankitwanit, Andrzej Rajca

  • 1Department of Chemistry, University of Nebraska , Lincoln, Nebraska 68588-0304, United States.

The Journal of Organic Chemistry
|January 10, 2015
PubMed
Summary
This summary is machine-generated.

Stable high-spin organic molecules are now rationally designed for applications in organic magnetism, MRI contrast agents, and spintronics. This synopsis reviews factors influencing high-spin states and recent synthetic advancements.

More Related Videos

High-Temperature and High-Pressure In situ Magic Angle Spinning Nuclear Magnetic Resonance Spectroscopy
08:55

High-Temperature and High-Pressure In situ Magic Angle Spinning Nuclear Magnetic Resonance Spectroscopy

Published on: October 9, 2020

6.2K
Molecular Entanglement and Electrospinnability of Biopolymers
07:59

Molecular Entanglement and Electrospinnability of Biopolymers

Published on: September 3, 2014

15.2K

Related Experiment Videos

Last Updated: Apr 18, 2026

Light-driven Molecular Motors on Surfaces for Single Molecular Imaging
08:40

Light-driven Molecular Motors on Surfaces for Single Molecular Imaging

Published on: March 13, 2019

12.2K
High-Temperature and High-Pressure In situ Magic Angle Spinning Nuclear Magnetic Resonance Spectroscopy
08:55

High-Temperature and High-Pressure In situ Magic Angle Spinning Nuclear Magnetic Resonance Spectroscopy

Published on: October 9, 2020

6.2K
Molecular Entanglement and Electrospinnability of Biopolymers
07:59

Molecular Entanglement and Electrospinnability of Biopolymers

Published on: September 3, 2014

15.2K

Area of Science:

  • Organic Chemistry
  • Materials Science

Background:

  • High-spin organic molecules offer potential in magnetism, MRI contrast agents, and spintronics.
  • Previously considered transient, these molecules can now be synthesized with stability.

Purpose of the Study:

  • To provide an overview of factors leading to high-spin ground states in organic molecules.
  • To summarize recent progress in the design and synthesis of stable high-spin organic molecules.

Main Methods:

  • Review of theoretical principles governing high-spin states.
  • Analysis of synthetic strategies for stable high-spin organic molecule construction.

Main Results:

  • Identification of key molecular design principles for achieving high-spin states.
  • Demonstration of successful synthesis and characterization of stable high-spin organic compounds.

Conclusions:

  • Rational design enables the creation of stable high-spin organic molecules.
  • These molecules hold significant promise for advanced technological applications.