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Septic Arthritis of the Elbow in Children: Clinical Presentation and Microbiological Profile
Afamefuna M Nduaguba1, John M Flynn, Wudbhav N Sankar
1Children's Hospital of Philadelphia, Philadelphia, PA.
Insights
Pediatric elbow septic arthritis is often diagnosed late and commonly involves osteomyelitis. Staphylococcus aureus is the most frequent pathogen, highlighting the need for prompt diagnosis and imaging like MRI.
Area of Science:
- Pediatric Orthopedics
- Pediatric Infectious Diseases
- Musculoskeletal Infections
Background:
- Septic arthritis of the elbow in children is a rare but significant musculoskeletal infection.
- Limited published data exists to guide clinical management.
- This study aims to characterize the clinical presentation, diagnostics, pathology, and microbiology of pediatric elbow septic arthritis.
Purpose of the Study:
- To describe the clinical presentation and diagnostic findings.
- To identify associated pathology.
- To determine the microbiological profile of septic arthritis of the elbow in children.
Main Methods:
- Retrospective analysis of children with elbow arthrocentesis for presumed septic arthritis and positive microbial growth.
- Data collection included demographics, signs, symptoms, imaging, and laboratory results.
- Study design was a Level IV case series.
Main Results:
- Twelve children (average age 6 years, 9 months) were included.
- Common symptoms included pain, erythema, edema, and restricted motion; 10/12 were febrile.
- Concurrent osteomyelitis was present in 7 patients; Staphylococcus aureus (MSSA and MRSA) was the most common pathogen (9/12).
- Elevated inflammatory markers (ESR, CRP) and synovial WBC counts were noted.
- One patient developed fulminant sepsis, and two were readmitted for osteomyelitis or recurrent septic arthritis.
Conclusions:
- Staphylococcus aureus is the predominant pathogen in pediatric elbow septic arthritis.
- Diagnosis is frequently delayed, with common elevation of inflammatory markers.
- Concomitant osteomyelitis is frequent, suggesting MRI should be considered in the diagnostic work-up.
Background:
Septic arthritis of the elbow in children is a rare but important musculoskeletal infection, and there is little published data to guide treating clinicians. The purpose of this study was to describe the clinical presentation and diagnostic findings, associated pathology, and microbiological profile of septic arthritis of the elbow in a pediatric population.
Methods:
We retrospectively analyzed a consecutive series of children who had an elbow arthrocentesis for presumed septic arthritis and whose joint aspirates were positive for microbial growth. Data collected included demographics, presenting signs and symptoms, imaging, and laboratory data, including culture results.
Results:
Twelve children underwent diagnostic arthrocentesis of the elbow joint for septic arthritis at an average age of 6 years and 9 months (range, 2 mo to 13 y and 7 mo). Every child had pain, localized erythema and edema, and restricted range of motion; 10/12 were febrile. Mean duration of symptoms prior to joint tap was 4 days (range, 1 to 14 d). Concurrent osteomyelitis was found in 7 patients, as confirmed with magnetic resonance imaging (MRI): 5 at initial presentation and 2 after readmission for persistent symptoms. Causative pathogens were MSSA (7), MRSA (2), Group G streptococcus (1), Pseuodomonas aureginosa (1), and Streptococcus pneumonia (1). ESR was >40 mm/h in 8/11 patients, CRP was >2 mg/dL in all patients, and synovial WBC count was >50,000 cells/mm in 8/9 patients. One patient developed fulminant sepsis during hospitalization and 2 children were readmitted within 30 days of discharge for unrecognized osteomyelitis and/or recurrence of septic arthritis of the elbow.
Conclusion:
In 12 children studied with septic arthritis, S. aureus was the most common pathogen. Diagnosis is often delayed, and in most cases inflammatory markers were elevated (ESR>40 mm/h, CRP>2 mg/dL). Concomitant osteomyelitis is quite common, and therefore magnetic resonance imaging should be considered as part of the diagnostic work-up for this condition.
Level Of Evidence:
Level IV—Case series.
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