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Related Concept Videos

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

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Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
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Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping
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Predicting stroke outcome using clinical- versus imaging-based scoring system.

Joon Hyun Baek1, Kitae Kim1, Yeong-Bae Lee1

  • 1Department of Neurology, Gachon University Gil Medical Center, Incheon, South Korea.

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
|January 11, 2015
PubMed
Summary
This summary is machine-generated.

Alberta Stroke Program Early Computed Tomography (CT) Score (ASPECTS) is superior to the DRAGON score for predicting functional outcomes in ischemic stroke patients treated with intravenous alteplase. This imaging-based score offers better predictability for patient recovery.

Keywords:
ASPECTS scoreCerebral infarctDRAGON scoreoutcomesprognosisthrombolysis

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Area of Science:

  • Neurology
  • Radiology
  • Clinical Medicine

Background:

  • Predicting outcomes in ischemic stroke patients receiving intravenous alteplase is crucial.
  • Existing models include clinical-based and imaging-based systems.
  • Alberta Stroke Program Early Computed Tomography (CT) Score (ASPECTS) and DRAGON score are key examples.

Purpose of the Study:

  • To compare the predictability of stroke outcome between the clinical (DRAGON) and imaging (ASPECTS)-based scoring systems.
  • To evaluate the performance of ASPECTS and DRAGON in predicting good functional outcome after stroke.
  • To identify independent predictors of good prognosis in acute ischemic stroke patients.

Main Methods:

  • Analysis of 120 patients with middle cerebral artery territory stroke treated with i.v. alteplase.
  • Comparison of ASPECTS and DRAGON scores using Pearson correlation and AUC-ROC analysis.
  • Multiple regression analysis to assess predicting power of clinical factors and scoring systems.

Main Results:

  • Both ASPECTS (r = -.841) and DRAGON (r = .657) significantly correlated with good functional outcome.
  • ASPECTS (AUC-ROC, .972) was significantly superior to DRAGON (AUC-ROC, .854) in predicting functional outcome.
  • ASPECTS was an independent predictor of good prognosis (OR, 6.59 per 1-point increase).

Conclusions:

  • ASPECTS is a superior method for predicting functional outcome in acute ischemic stroke patients receiving i.v. alteplase compared to DRAGON.
  • Integrating ASPECTS into clinical care pathways can aid decision-making for stroke treatment.
  • Imaging-based assessment using ASPECTS offers enhanced predictive value for patient recovery.