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Updated: Apr 18, 2026

A Mouse Model to Assess Innate Immune Response to Staphylococcus aureus Infection
Published on: February 28, 2019
[Aspects of the innate immune response to intramammary Staphylococcus aureus infections in cattle]
Elizabet A L Pereyra1, Bibiana E Dallard1, Luis F Calvinho2
1Laboratorio de Biología Celular y Molecular Aplicada, Facultad de Ciencias Veterinarias, Universidad Nacional del Litoral (UNL), Santa Fe, Argentina; Instituto de Ciencias Veterinarias del Litoral (ICIVET-Litoral), UNL-Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Santa Fe, Argentina.
Abstract:
Staphylococcus aureus is the pathogen most frequently isolated from bovine mastitis worldwide, causing chronic intramammary infections that limit profitable dairying. The objective of this article is to characterize the mechanisms involved in S. aureus mammary gland infections considering two different aspects of the infectious process; on the one hand, the aspects involved in the host innate immune response and on the other hand, the capacity of this organism to evade the immune system and interact with different cell types. The exploration of S. aureus interactions with the immune response of bovine mammary gland will help identify targets to outline new preventive or curative alternatives for intramammary infections caused by this organism.
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