Adalimumab treatment for hidradenitis suppurativa associated with Crohn's disease
Dominika Diamantova1, Iva Lomickova, Petra Cetkovska
1Dominka Diamantova, MD, Department of Dermatology and Venereology, Military Hospital, Sišilovo nam. 7, Olomouc, Czech Republic; DominikaDiamantova@seznam.cz.
Insights
Hidradenitis suppurativa (HS), an inflammatory condition, and Crohn's disease (CD) can co-occur. Adalimumab effectively treated a patient with both refractory conditions, suggesting its potential for HS management.
Area of Science:
- Dermatology
- Gastroenterology
- Immunology
Background:
- Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition.
- Crohn's disease (CD) is a chronic inflammatory bowel disease.
- A documented association exists between HS and CD.
Observation:
- A case report details a patient with co-existing CD and HS.
- The patient's condition was refractory to various treatments.
- Adalimumab was administered to the patient.
Findings:
- Complete resolution of both HS and CD was observed.
- Adalimumab demonstrated efficacy in this patient.
- This suggests a potential therapeutic role for adalimumab in HS.
Implications:
- This case supports the co-occurrence of HS and CD.
- Adalimumab, approved for CD, may be a safe and effective treatment for HS.
- Further research into adalimumab for HS is warranted.
Abstract:
Hidradenitis suppurativa (HS) is a chronic, inflammatory disease characterized by recurring abscesses, nodules, and fistulas predominantly in the area of the groin and axillae. The association between HS and Crohn's disease (CD) has already been documented. We report on a case of a patient with CD associated HS, refractory to multiple local and systemic agents.A complete resolution of both diseases was finally achieved after treatment with adalimumab. Our case report supports the co-occurrence of both diseases and suggests that adalimumab approved for CD might also be a safe and effective therapeutic option in the treatment of HS.
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