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Updated: Apr 18, 2026

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Detecting the Ligand-binding Domain Dimerization Activity of Estrogen Receptor Alpha Using the Mammalian Two-Hybrid Assay
Published on: December 19, 2018
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Luminescent Ag6Au6 heterometallic ethisterone cluster and probe for estrogen receptor α
Wen-Jing Guo1, Yong-Tao Wang, De-Xian Kong
1Ministry of Education, Fujian Provincial Key Lab of Analysis and Detection for Food Safety and Institute of Nanomedicine and Nanobiosensing, College of Chemistry, Fuzhou University, Fuzhou, Fujian 350108 (P. R. China).
Chemistry (Weinheim an Der Bergstrasse, Germany)
|January 13, 2015
Abstract:
A heterometallic cluster [Ag6Au6(ethisterone)12] of an unprecedented topology was synthesized and characterized. A sensitive and specific probe for estrogen receptor α (ERα) has been developed for the first time based on the enhancement of the Ag6Au6 luminescence.

