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Related Concept Videos

Graves' Disease I: Introduction01:28

Graves' Disease I: Introduction

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Graves' disease is an autoimmune disorder that causes hyperthyroidism, or overactivity of the thyroid gland. It results from autoantibodies called thyroid-stimulating immunoglobulins (TSIs), which bind to thyroid-stimulating hormone (TSH) receptors, leading to overstimulation of hormone production and a hypermetabolic state.EtiologyAlthough considered idiopathic, Graves’ disease has well-established contributing factors. There is a strong genetic component, with increased prevalence...
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Graves Disease II: Pathophysiology01:24

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Graves’ disease is an autoimmune disorder characterized by the production of thyroid-stimulating immunoglobulins (TSI) that activate TSH receptors, leading to excessive synthesis and release of thyroid hormones (T3 and T4) and resulting in hyperthyroidism.Among all causes of hyperthyroidism, Graves’ disease is the most common and can happen at any age, though it is more frequent in women. It produces a hypermetabolic state with features such as weight loss, tachycardia, tremor,...
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Hyperthyroidism I: Introduction01:25

Hyperthyroidism I: Introduction

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Hyperthyroidism is a type of thyrotoxicosis characterized by the thyroid gland's overproduction of the thyroid hormones triiodothyronine (T3) and thyroxine (T4). This hormone excess increases the basal metabolic rate and enhances sensitivity to catecholamines.DiagnosisDiagnosis is based on clinical features and biochemical testing. It typically shows suppressed thyroid-stimulating hormone (TSH) levels below 0.4 mIU/L, with elevated free T3 and/or T4. Additional tests, including thyroid...
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Hyperthyroidism II: Pathophysiology01:27

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Hyperthyroidism is a hypermetabolic state caused by elevated levels of thyroid hormones, triiodothyronine (T3) and thyroxine (T4). It results from dysregulation at the thyroid, pituitary, or immune system level and affects multiple organ systems.PathophysiologyThe most common cause of hyperthyroidism is Graves’ disease, an autoimmune disorder in which antibodies, specifically thyroid-stimulating antibodies (TSAb), a subtype of TSH receptor antibodies (TRAb), bind to and activate TSH...
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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Goiter refers to an abnormal enlargement of the thyroid gland that may appear as a diffuse goiter (uniform enlargement) or nodular (single or multiple nodules). Functionally, it is classified as nontoxic (normal/low hormone levels) or toxic (excess hormone production).PathophysiologyDiffuse thyroid enlargement typically results from prolonged stimulation by thyroid-stimulating hormone (TSH) or TSH-like agents, commonly seen in hypothyroidism or iodine deficiency. In contrast, in hyperthyroid...
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Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
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Cutaneous manifestations associated with thyroid disease.

Daciana Elena Brănişteanu1, Andreea Dimitriu, Mioara Vieriu

  • 1University of Medicine and Pharmacy Grigore T. Popa - Iaşi, Department of Medical Specialties (II).

Revista Medico-Chirurgicala a Societatii De Medici Si Naturalisti Din Iasi
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Summary

Thyroid diseases are linked to skin conditions like alopecia areata and lichen planus. Regular thyroid testing is recommended for patients with these dermatologic disorders.

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Area of Science:

  • Endocrinology
  • Dermatology
  • Internal Medicine

Background:

  • Thyroid diseases are common endocrine disorders.
  • Dermatologic manifestations can be indicators of underlying thyroid dysfunction.
  • Understanding this association is crucial for comprehensive patient care.

Purpose of the Study:

  • To detail the clinical and laboratory features of patients with dermatologic disorders linked to thyroid diseases.
  • To outline diagnostic criteria, treatments, and their effectiveness.
  • To highlight the association between specific thyroid conditions and skin ailments.

Main Methods:

  • Retrospective analysis of medical records from a university hospital's Dermato venereology Clinic.
  • Inclusion of patients diagnosed with thyroid diseases between January 2012 and December 2013.
  • Review of clinical data, investigations, treatments, and co-existing conditions.

Main Results:

  • 38 patients (36 female, 2 male) were studied.
  • Autoimmune thyroiditis (63%) was the most prevalent thyroid condition.
  • Alopecia areata (22%) and lichen planus (18%) were the most frequent dermatologic disorders.

Conclusions:

  • A significant association exists between specific dermatologic disorders and thyroid diseases.
  • Periodic thyroid function tests are advised for patients with associated skin conditions.
  • Early detection and management of thyroid dysfunction can impact dermatologic health.