The correlation between the ankle-brachial index and the metabolic syndrome.

F Mitu1, O Mitu, Maria-Magdalena Leon

  • 1University of Medicine and Pharmacy Grigore T. Popa - Iaşi, Department of Medical Specialties (I).

Insights

The ankle-brachial index effectively predicts cardiovascular disease risk, especially in patients with metabolic syndrome. Routine measurement can aid early diagnosis of atherosclerosis and high-risk individuals.

Area of Science:

  • Vascular Medicine
  • Cardiology
  • Public Health

Background:

  • Cardiovascular diseases (CVDs) are a leading cause of global mortality and disability.
  • Atherosclerosis is a primary etiological factor, with lower limb artery involvement indicating potential systemic vascular disease.
  • Metabolic syndrome and conventional risk factors significantly contribute to CVD development.

Purpose of the Study:

  • To evaluate correlations between ankle-brachial index (ABI) levels and cardiovascular risk factors.
  • To assess the relationship between ABI and metabolic syndrome.
  • To determine ABI's predictive value for cardiovascular disease.

Main Methods:

  • Ankle-brachial index (ABI) values categorized as normal or abnormal.
  • Evaluation of cardiovascular risk factors including age, sex, hypertension, obesity, smoking, dyslipidemia, and hyperglycemia.
  • Statistical analysis to compare ABI groups and identify correlations.

Main Results:

  • Significant statistical differences in ABI values were observed between normal and abnormal groups, particularly in patients with diabetes mellitus and metabolic syndrome.
  • The ankle-brachial index was found to be considerably lower in patients diagnosed with metabolic syndrome.
  • ABI demonstrated a strong association with metabolic syndrome and diabetes.

Conclusions:

  • Ankle-brachial index measurement serves as an independent predictor of cardiovascular disease development, beyond metabolic syndrome and conventional risk factors.
  • ABI is a valuable atherosclerosis marker for lower limb arteries.
  • Routine ABI measurement in clinical practice can facilitate early diagnosis of high-risk cardiovascular disease patients.
Abstract

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