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Five population-based interventions for smoking cessation: a MOST trial.

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  • 1Center for Tobacco Research and Intervention, University of Wisconsin School of Medicine and Public Health, 1930 Monroe Street, Suite 200, Madison, WI 53711 USA.

Translational Behavioral Medicine
|January 14, 2015
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Summary
This summary is machine-generated.

The National Cancer Institute's (NCI) Web site and nicotine replacement therapy (NRT) effectively increased smoking abstinence. However, the NCI Web site was less effective when combined with email messages.

Keywords:
MOST researchNicotine replacementSmoking cessationTelephone quitlineWeb site evaluation

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Area of Science:

  • Public Health
  • Behavioral Science
  • Health Communication

Background:

  • Understanding the effectiveness of various smoking cessation interventions is crucial for public health.
  • Few studies have examined the combined and interactive effects of multiple population-based smoking cessation strategies.

Purpose of the Study:

  • To evaluate the individual and interactive effects of five distinct smoking cessation interventions.
  • To assess the efficacy of the National Cancer Institute's (NCI) Web site, telephone quitlines, brochures, email messages, and nicotine replacement therapy (NRT).

Main Methods:

  • Utilized the multiphase optimization strategy (MOST) with 1,034 smokers recruited via smokefree.gov.
  • Employed a randomized factorial design, assigning participants to "on" or "off" conditions for each intervention.
  • Interventions included the NCI Web site, quitline counseling, brochures, motivational emails, and mini-lozenge NRT.

Main Results:

  • The NCI Web site and NRT significantly increased smoking abstinence.
  • The NCI Web site's effectiveness was diminished when used concurrently with motivational email messages.
  • Telephone quitlines, brochures, and email messages showed limited evidence of effectiveness on their own.

Conclusions:

  • The NCI Web site (www.smokefree.gov) and mailed nicotine mini-lozenges are effective population-based smoking cessation interventions.
  • Interactions between interventions, such as the NCI Web site and email messaging, can influence overall effectiveness.
  • Further research is needed to optimize combinations of smoking cessation strategies.