Related Experiment Video
Updated: Apr 18, 2026

Neonatal Pial Surface Electroporation
Published on: May 7, 2014
Congenital porencephaly in a new born child
Suthar Pokhraj P1, Patel Jigar J2, Mehta Chetan3
1Resident Doctor, Department of Radiology, S.S.G. Hospital, Medical College , Vadodara, Gujarat, India .
Insights
A newborn presented with an enlarged head and seizures due to a large cystic lesion in the brain. This fluid-filled lesion communicated with the ventricles and subarachnoid space, indicating a significant congenital abnormality.
Area of Science:
- Pediatric Neurology
- Neuroimaging
- Congenital Neurological Disorders
Background:
- Neonatal presentation of neurological abnormalities requires prompt diagnosis.
- Enlarged head circumference (macrocephaly) and seizures in newborns can indicate underlying structural brain abnormalities.
Purpose of the Study:
- To report a case of a large cystic lesion in a neonate.
- To highlight the neuroimaging findings in a congenital brain anomaly.
Main Methods:
- Case presentation of a 2-day-old male infant.
- Clinical examination including head circumference measurement and fontanelle assessment.
- Computed Tomography (CT) head imaging to evaluate brain structure.
Main Results:
- The infant presented with macrocephaly (56 cm head circumference) and seizures since birth.
- CT head revealed a large, non-enhancing, fluid-attenuating cystic lesion in the posterior parietal and occipital regions.
- The cystic lesion was observed to communicate with dilated bilateral lateral ventricles and the subarachnoid space.
Conclusions:
- A large cystic lesion communicating with the ventricular and subarachnoid spaces can cause significant neurological symptoms in neonates.
- CT head imaging is crucial for diagnosing such congenital cystic brain abnormalities.
Abstract:
A 2-day-old male child presented with history of enlarged head and seizures since birth, born by caesarean section. Head circumference was 56 cm (dilated) with widely open anterior and posterior fontanelle. Routine investigations were within normal limits. CT head revealed a large non-enhancing fluid attenuating cystic lesion in posterior parietal and occipital region with communicating to dilated bilateral lateral ventricles and subarachnoid space.

