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Association between asthma and risk of developing obstructive sleep apnea
Mihaela Teodorescu1, Jodi H Barnet2, Erika W Hagen2
1James B. Skatrud Pulmonary/Sleep Research Laboratory, William S. Middleton Memorial Veteran's Hospital, Madison, Wisconsin2Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison3Center for Sleep Medicine and Sleep Re.
JAMA
|January 14, 2015
Summary
Asthma is linked to a higher risk of developing obstructive sleep apnea (OSA). This study found that individuals with asthma were more likely to develop new-onset OSA, especially with longer asthma duration.
Area of Science:
- Respiratory Medicine
- Sleep Medicine
- Epidemiology
Background:
- Obstructive sleep apnea (OSA) is frequently observed in asthma patients, but a causal link remains unclear.
- Understanding the relationship between asthma and OSA development is crucial for patient care.
Purpose of the Study:
- To prospectively investigate the association between asthma and the incidence of obstructive sleep apnea (OSA).
Main Methods:
- A population-based prospective cohort study (Wisconsin Sleep Cohort Study) followed participants over 4-year intervals.
- Asthma status was assessed via questionnaires, and OSA incidence was determined by polysomnography.
- Repeated-measures Poisson regression was used to analyze the association between asthma and incident OSA, adjusting for confounders.
Main Results:
- Participants with asthma had a significantly increased risk of developing new-onset OSA (adjusted RR, 1.39).
- Asthma was also associated with a higher risk of OSA accompanied by habitual sleepiness (adjusted RR, 2.72).
- Longer asthma duration correlated with increased incidence of both OSA and OSA with sleepiness.
Conclusions:
- Asthma is a significant risk factor for the development of obstructive sleep apnea.
- Further research into the underlying mechanisms and the need for OSA screening in asthma patients is recommended.
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