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Sequence of rat skeletal muscle phosphoglycerate mutase cDNA
J Castellà-Escolà1, L Montoliu, G Pons
1Unitat de Bioquímica, Facultat de Medicina, Universitat de Barcelona, Spain.
Biochemical and Biophysical Research Communications
|December 29, 1989
Abstract:
A cDNA clone coding rat skeletal muscle phosphoglycerate mutase was isolated from a rat muscle lambda gt10 cDNA library and its sequence was determined. The deduced protein possesses 252 amino acids and is 94% homologous with respect to human muscle phosphoglycerate mutase. No amino acids changes occur at the active site and structural predictions suggest strong conformational homologies with other enzymes of the mutase family.