Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Raman Spectroscopy Instrumentation: Overview01:26

Raman Spectroscopy Instrumentation: Overview

1.9K
A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...
1.9K
Confocal Fluorescence Microscopy01:16

Confocal Fluorescence Microscopy

22.2K
Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
22.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

5,6-Fused heterocycle cholate derivatives as spore germination inhibitors of Clostridioides difficile.

Bioorganic & medicinal chemistry·2026
Same author

Standoff real-time detection of floating and submerged objects in ocean water.

Scientific reports·2025
Same author

Standoff ultra-compact micro-Raman (SUCR) sensor for lunar surface exploration.

Optics express·2025
Same author

Half-Inch Monolithic Spatial Heterodyne Raman Spectrometer: A Study of Polarized Raman Spectra of Organic Liquids and Instrumental Performance.

Applied spectroscopy·2024
Same author

Crebinostat facilitates memory formation.

Biochemical and biophysical research communications·2024
Same author

Effect of Lower Extremity Nerve Decompression in Patients With Painful Diabetic Peripheral Neuropathy: The Diabetic Neuropathy Nerve Decompression Randomized, Observation Group and Placebo Surgery-Controlled Clinical Trial.

Annals of surgery·2024

Related Experiment Video

Updated: Apr 18, 2026

Femtosecond Laser Filaments for Use in Sub-Diffraction-Limited Imaging and Remote Sensing
06:16

Femtosecond Laser Filaments for Use in Sub-Diffraction-Limited Imaging and Remote Sensing

Published on: April 25, 2019

8.1K

Next generation laser-based standoff spectroscopy techniques for Mars exploration.

Patrick J Gasda1, Tayro E Acosta-Maeda, Paul G Lucey

  • 1Hawai'i Institute for Geophysics and Planetology, University of Hawai'i, Mānoa, 1680 East West Road, Honolulu, Hawai'i 96822 USA.

Applied Spectroscopy
|January 15, 2015
PubMed
Summary
This summary is machine-generated.

A new laser-induced spectroscopy instrument, QuaLITy, enhances Mars exploration by detecting elements and biosignatures with high efficiency and sensitivity. This advanced technology meets NASA

More Related Videos

Laser-induced Breakdown Spectroscopy: A New Approach for Nanoparticle's Mapping and Quantification in Organ Tissue
10:17

Laser-induced Breakdown Spectroscopy: A New Approach for Nanoparticle's Mapping and Quantification in Organ Tissue

Published on: June 18, 2014

14.3K
Direct Comparison of Hyperspectral Stimulated Raman Scattering and Coherent Anti-Stokes Raman Scattering Microscopy for Chemical Imaging
09:46

Direct Comparison of Hyperspectral Stimulated Raman Scattering and Coherent Anti-Stokes Raman Scattering Microscopy for Chemical Imaging

Published on: April 28, 2022

5.1K

Related Experiment Videos

Last Updated: Apr 18, 2026

Femtosecond Laser Filaments for Use in Sub-Diffraction-Limited Imaging and Remote Sensing
06:16

Femtosecond Laser Filaments for Use in Sub-Diffraction-Limited Imaging and Remote Sensing

Published on: April 25, 2019

8.1K
Laser-induced Breakdown Spectroscopy: A New Approach for Nanoparticle's Mapping and Quantification in Organ Tissue
10:17

Laser-induced Breakdown Spectroscopy: A New Approach for Nanoparticle's Mapping and Quantification in Organ Tissue

Published on: June 18, 2014

14.3K
Direct Comparison of Hyperspectral Stimulated Raman Scattering and Coherent Anti-Stokes Raman Scattering Microscopy for Chemical Imaging
09:46

Direct Comparison of Hyperspectral Stimulated Raman Scattering and Coherent Anti-Stokes Raman Scattering Microscopy for Chemical Imaging

Published on: April 28, 2022

5.1K

Area of Science:

  • Planetary Science
  • Astrobiology
  • Spectroscopy

Background:

  • NASA's Mars 2020 mission requires instruments for fine-scale elemental and biosignature detection.
  • The Mars Science Laboratory Curiosity's ChemCam (Chemistry Camera) demonstrated the feasibility of laser-induced spectroscopy for space exploration.
  • Existing methods like Alpha Particle X-Ray Spectrometer are complemented by laser-induced spectroscopy.

Purpose of the Study:

  • To develop a highly efficient remote laser-induced spectroscopy instrument for Mars exploration.
  • To meet NASA's requirements for detecting elements, minerals, and biosignatures at fine scales.
  • To improve upon existing laser-induced spectroscopy capabilities for space missions.

Main Methods:

  • Development of a prototype remote LIBS-Raman-fluorescence instrument named QuaLITy.
  • Utilizing a directly coupled system, an intensified charge-coupled device image detector, and a pulsed laser for time-resolved measurements.
  • Comparison of QuaLITy's LIBS capabilities with a commercial spectrometer at distances of 7m and 5m.

Main Results:

  • The QuaLITy instrument demonstrated approximately 70,000 times greater signal recording efficiency compared to commercial LIBS instruments.
  • Achieved an order of magnitude increase in signal-to-noise ratio for quantitative elemental analysis.
  • Enabled LIBS with 200-300 μm spatial resolution at 7m, Raman with 1 mm resolution at 3m, and long-distance bioorganic fluorescence detection.

Conclusions:

  • The QuaLITy instrument significantly enhances detection limits and sensitivity for elemental and biosignature analysis.
  • The developed instrument fulfills NASA's expectations for advanced Mars exploration tools.
  • QuaLITy offers a reliable and efficient method for in-situ analysis of extraterrestrial samples.