The next-generation ALK inhibitors.

Georg Pall1

  • 1Department of Internal Medicine, Hematology/Oncology, University Hospital Innsbruck, Innsbruck, Austria.

Summary

Second-generation ALK inhibitors are emerging to combat crizotinib resistance in ALK-rearranged lung cancer. These new drugs show promise, but optimal clinical integration requires careful trial design and patient selection.

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