[Benign solitary thyroid nodule (BSTN)]

Out of a series of 210 patients (193 women and 17 men) with BSTN, 62% presented an warm nodule, 25.2% a hot nodule and 11.9% a cold nodule. The highest incidence of the nodule was noticed round the age of 40-50 years. The most common site was the middle and lower area of the right thyroid lobe. The thyroid scintigram provided orientative data regarding the nature of BSTN, the treatment indication being the surgical intervention. Histopathologically, polymorphic aspects ranging from anizofollicular adenoma, adenomatous proliferations areas and hyperfunctional aspect to degenerative sclerous alterations and lymphoplasmocitary infiltrations were noticed. The current hypotheses regarding the etiopathogeny of nodule forming process are discussed. Based on some data in the literature, we consider the nodularization of the thyroid gland as a reactional zone functional desynchronization in the conditions of some great variations of the iodate intaxe.