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Updated: Apr 18, 2026

05:17
Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
Published on: February 9, 2021
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[2-R-mercapto-1, 3, 4-thyadiazol derivates having biological activity. Note I]
T Sauciuc1, Z Cojocaru, V Zvorişteanu
1Institutul de medicină şi farmacie Iaşi.
Abstract:
The importance of 1,3,4-thyadiazol nucleus is illustrated by the fact that it enters the structure of many compounds having different biological activities. In this paper the results of some investigations for obtaining new derivates of 1,3,4-thydiazol 2,5 distributed are presented. Based upon the presented diagram 13 2-R-5-mercapto-1,3,4-thyadiazols, analysed both physico-chemically and biologically were synthetized.

